[Venlafaxine withdrawal syndrome: report of six cases and review of the literature]

V Pinzani; E Giniès; L Robert; H Peyrière; M Abbar; J P Blayac

doi:10.1016/s0248-8663(00)80048-x

[Venlafaxine withdrawal syndrome: report of six cases and review of the literature]

Rev Med Interne. 2000 Mar;21(3):282-4. doi: 10.1016/s0248-8663(00)80048-x.

[Article in French]

Authors

V Pinzani¹, E Giniès, L Robert, H Peyrière, M Abbar, J P Blayac

Affiliation

¹ Centre régional de pharmacovigilance, CHU de Montpellier, Montpellier, France.

PMID: 10763190
DOI: 10.1016/s0248-8663(00)80048-x

Abstract

Introduction: Venlafaxine is an antidepressant that selectively inhibits serotonin reuptake and is a norepinephrine inhibitor. Withdrawal syndromes can occur after abrupt drug discontinuation of long-term regimens.

Exegesis: We report six cases of withdrawal symptoms after venlafaxine discontinuation.

Conclusion: Physicians must be aware of the frequency, rapidity and potent severity of these withdrawal syndromes.

Publication types

Case Reports
English Abstract
Review

MeSH terms

Adult
Akathisia, Drug-Induced / etiology
Antidepressive Agents, Second-Generation / adverse effects*
Cyclohexanols / adverse effects*
Depressive Disorder / drug therapy
Fatigue / chemically induced
Female
Gastrointestinal Diseases / chemically induced
Hallucinations / chemically induced
Headache / chemically induced
Humans
Male
Middle Aged
Paresthesia / chemically induced
Selective Serotonin Reuptake Inhibitors / adverse effects*
Substance Withdrawal Syndrome / diagnosis
Substance Withdrawal Syndrome / etiology*
Time Factors
Venlafaxine Hydrochloride

Substances

Antidepressive Agents, Second-Generation
Cyclohexanols
Serotonin Uptake Inhibitors
Venlafaxine Hydrochloride