Acute transient myopia induced by indapamide

Am J Ophthalmol. 2000 Apr;129(4):538-40. doi: 10.1016/s0002-9394(99)00402-x.

Abstract

Purpose: To report on a case of acute transient myopia associated with ciliochoroidal detachment induced by indapamide.

Method: Case report. Clinical examination, ultrasonography, and fluorescein angiography were performed during the acute phase of disease and convalescence.

Results: After indapamide was discontinued, acute bilateral myopia, which was associated with anterior chamber shallowing and diffuse choroidal thickening, resolved spontaneously 8 days after onset. The initial angiography showed scattered islands of delayed fluorescein filling that disappeared without any permanent change by day 30.

Conclusion: Indapamide can induce spontaneously resolving transient myopia associated with diffuse choroidal thickening.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Antihypertensive Agents / adverse effects*
  • Choroid Diseases / chemically induced
  • Choroid Diseases / diagnosis
  • Choroid Diseases / physiopathology
  • Fluorescein Angiography
  • Humans
  • Indapamide / adverse effects*
  • Male
  • Myopia / chemically induced*
  • Myopia / diagnosis
  • Myopia / physiopathology

Substances

  • Antihypertensive Agents
  • Indapamide