Concurrent chemoimmunotherapy in metastatic clear cell sarcoma: a case report

Tumori. 1999 Nov-Dec;85(6):512-4. doi: 10.1177/030089169908500617.

Abstract

Clear cell sarcoma is a rare tumor with a poor prognosis. The therapeutic approach in the metastatic disease stage is controversial: to the authors' knowledge the use of concurrent chemoimmunotherapy has not been previously reported. We present a case of a 57-year-old male with metastatic clear cell sarcoma treated simultaneously with subcutaneous interferon-a 2b and six courses of chemotherapy according to the CyVEDIC regimen. Disease stabilization lasting 17 months was achieved.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Cyclophosphamide / administration & dosage
  • Dacarbazine / administration & dosage
  • Disease Progression
  • Epirubicin / administration & dosage
  • Fatal Outcome
  • Humans
  • Immunotherapy / methods*
  • Interferon alpha-2
  • Interferon-alpha / therapeutic use*
  • Leg
  • Lung Neoplasms / complications
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / secondary
  • Lung Neoplasms / therapy*
  • Male
  • Middle Aged
  • Pleural Effusion, Malignant / etiology*
  • Recombinant Proteins
  • Sarcoma, Clear Cell / drug therapy
  • Sarcoma, Clear Cell / pathology
  • Sarcoma, Clear Cell / therapy*
  • Treatment Outcome
  • Vincristine / administration & dosage

Substances

  • Interferon alpha-2
  • Interferon-alpha
  • Recombinant Proteins
  • Epirubicin
  • Vincristine
  • Dacarbazine
  • Cyclophosphamide

Supplementary concepts

  • CYVEDIC protocol