Structural analysis of the complex of a distamycin analogue with the Dickerson dodecamer 13C labeled at 5'-carbons using NMR spectroscopy

E Kawashima; N Shimba; E Suzuki; Y Ishido

doi:10.1093/nass/42.1.187

Structural analysis of the complex of a distamycin analogue with the Dickerson dodecamer 13C labeled at 5'-carbons using NMR spectroscopy

Nucleic Acids Symp Ser. 1999:(42):187-8. doi: 10.1093/nass/42.1.187.

Authors

E Kawashima¹, N Shimba, E Suzuki, Y Ishido

Affiliation

¹ Laboratory of Pharmaceutical Chemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Hachioji, Japan.

PMID: 10780442
DOI: 10.1093/nass/42.1.187

Abstract

Structural analysis of the complex of a distamycin analogue (Tallimustine) with the Dickerson dodecamer d(C*G*C*G*A*A*T*T*C*G*C*G) [N*:[5'-(13)C]nucleotide] was performed by NMR spectroscopy and the results will be described in detail.

MeSH terms

Antineoplastic Agents, Alkylating / chemistry*
Base Sequence
Carbon Isotopes
Distamycins / chemistry*
Nitrogen Mustard Compounds / chemistry*
Nuclear Magnetic Resonance, Biomolecular
Oligodeoxyribonucleotides / chemistry*

Substances

Antineoplastic Agents, Alkylating
Carbon Isotopes
Distamycins
Nitrogen Mustard Compounds
Oligodeoxyribonucleotides
tallimustine