TRAIL receptor-2 signals apoptosis through FADD and caspase-8

Nat Cell Biol. 2000 Apr;2(4):241-3. doi: 10.1038/35008667.

Authors

J L Bodmer¹, N Holler, S Reynard, P Vinciguerra, P Schneider, P Juo, J Blenis, J Tschopp

Affiliation

¹ Institute of Biochemistry, University of Lausanne, BIL Biomedical Research Center, Chemin des Boveresses 155, CH-1066 Epalinges, Switzerland.

PMID: 10783243
DOI: 10.1038/35008667

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Apoptosis / physiology*
Arabidopsis Proteins*
Caspase 3
Caspase 8
Caspase 9
Caspases / metabolism*
Fatty Acid Desaturases / metabolism*
Humans
Jurkat Cells / chemistry
Jurkat Cells / cytology
Jurkat Cells / enzymology
Receptors, TNF-Related Apoptosis-Inducing Ligand
Receptors, Tumor Necrosis Factor / metabolism*
Signal Transduction / physiology*

Substances

Arabidopsis Proteins
Receptors, TNF-Related Apoptosis-Inducing Ligand
Receptors, Tumor Necrosis Factor
TNFRSF10B protein, human
Fatty Acid Desaturases
Fad7 protein, Arabidopsis
CASP3 protein, human
CASP8 protein, human
CASP9 protein, human
Caspase 3
Caspase 8
Caspase 9
Caspases