N-[[(5-methyl-3-phenylisoxazol-4-yl)-phenyl]sulfonyl]propanamide, sodium salt, parecoxib sodium: A potent and selective inhibitor of COX-2 for parenteral administration

J Med Chem. 2000 May 4;43(9):1661-3. doi: 10.1021/jm000069h.
No abstract available

MeSH terms

  • Acylation
  • Animals
  • Cyclooxygenase 2
  • Cyclooxygenase 2 Inhibitors
  • Cyclooxygenase Inhibitors / administration & dosage
  • Cyclooxygenase Inhibitors / pharmacology*
  • Dogs
  • Injections
  • Isoenzymes / antagonists & inhibitors*
  • Isoenzymes / pharmacology*
  • Isoxazoles / administration & dosage
  • Isoxazoles / pharmacology*
  • Macaca fascicularis
  • Male
  • Prostaglandin-Endoperoxide Synthases / pharmacology*
  • Rats

Substances

  • Cyclooxygenase 2 Inhibitors
  • Cyclooxygenase Inhibitors
  • Isoenzymes
  • Isoxazoles
  • parecoxib
  • Cyclooxygenase 2
  • Prostaglandin-Endoperoxide Synthases