[Akinetic mutism and progressive supranuclear palsy-like syndrome after the shunt of an obstructive hydrocephalus. Successful treatment with bromocriptine: 2 cases]

Rev Neurol (Paris). 2000 Apr;156(4):380-3.
[Article in French]

Abstract

Two cases of obstructive hydrocephalus who suffered multiple shunt failures and shunt revisions are presented. The patients developed after the neurochirurgical treatment a clinical syndrome of akinetic mutism followed by a Progressive Supranuclear Palsy-like (PSP) syndrome. The akinetic mutism and the PSP-like syndrome were remarkably improved with bromocriptine.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Akinetic Mutism / etiology*
  • Antiparkinson Agents / therapeutic use
  • Atrophy / diagnostic imaging
  • Atrophy / pathology
  • Bromocriptine / therapeutic use
  • Humans
  • Hydrocephalus / diagnosis
  • Hydrocephalus / surgery*
  • Male
  • Mesencephalon / diagnostic imaging
  • Mesencephalon / pathology
  • Neurosurgical Procedures
  • Severity of Illness Index
  • Supranuclear Palsy, Progressive / drug therapy
  • Supranuclear Palsy, Progressive / etiology*
  • Tomography, X-Ray Computed
  • Ventriculoperitoneal Shunt / adverse effects*

Substances

  • Antiparkinson Agents
  • Bromocriptine