T-cell memory: You must remember this .

Curr Biol. 2000 May 4;10(9):R338-40. doi: 10.1016/s0960-9822(00)00461-9.

Abstract

While antigen-inexperienced (naive) T cells appear to require constant tickling of their receptor by self-antigens for homeostasis, antigen-experienced (memory) T cells have no such requirement. An implication is that long-term T-cell memory does not depend on persisting antigen.

Publication types

  • Review

MeSH terms

  • Animals
  • CD8-Positive T-Lymphocytes / immunology*
  • Histocompatibility Antigens Class I / immunology
  • Humans
  • Immunologic Memory / immunology*
  • Interleukin-15 / immunology*
  • Receptors, Interleukin-15
  • Receptors, Interleukin-2 / immunology

Substances

  • Histocompatibility Antigens Class I
  • IL15RA protein, human
  • Interleukin-15
  • Receptors, Interleukin-15
  • Receptors, Interleukin-2