Objective: To analyze genetic polymorphism of D17S1290, D17S1293, D17S1303 and D17S1308 in Chinese Hans.
Methods: Fifty unrelated individuals were analyzed by PCR amplification fragment length polymorphism analysis method.
Results: 9, 7, 5, 5 alleles were observed at these 4 STR loci respectively, the genotypes distributions in Chinese Hans were in accordance with Hardy-Weinberg equilibrium, the expected heterozygosities for these loci were 0.770, 0.828, 0.608, 0.669 respectively, the polymorphism information contents(PIC) were 0.763, 0.820, 0.602, 0.662 respectively.
Conclusion: The results demonstrate these 4 STR loci can be used for genetic analysis.