Excessive portal venous supply of long-chain free fatty acids to the liver, leading to hypothalamus-pituitary-adrenal-axis and sympathetic activation as a key to the development of syndrome X. A proposed concept for the induction of syndrome X

Ann N Y Acad Sci. 1999 Nov 18:892:308-11. doi: 10.1111/j.1749-6632.1999.tb07804.x.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Diabetes Mellitus, Type 2 / metabolism
  • Fatty Acids, Nonesterified / blood*
  • Humans
  • Hypertension / metabolism
  • Hypothalamo-Hypophyseal System / metabolism*
  • Insulin Resistance*
  • Liver / metabolism*
  • Pituitary-Adrenal System / metabolism*
  • Portal Vein*
  • Sympathetic Nervous System / metabolism
  • Sympathetic Nervous System / physiopathology*

Substances

  • Fatty Acids, Nonesterified