HIF-1 is essential for multilineage hematopoiesis in the embryo

Adv Exp Med Biol. 2000:475:275-84. doi: 10.1007/0-306-46825-5_26.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Aryl Hydrocarbon Receptor Nuclear Translocator
  • Cell Hypoxia / genetics
  • Cell Hypoxia / physiology
  • Chimera
  • Colony-Forming Units Assay
  • Cytokines / pharmacology
  • DNA-Binding Proteins / genetics
  • DNA-Binding Proteins / physiology*
  • Embryonic and Fetal Development / drug effects
  • Embryonic and Fetal Development / genetics
  • Embryonic and Fetal Development / physiology
  • Endothelial Growth Factors / pharmacology
  • Female
  • Fetal Hypoxia / genetics
  • Fetal Hypoxia / physiopathology
  • Hematopoiesis / drug effects
  • Hematopoiesis / genetics
  • Hematopoiesis / physiology*
  • Hypoxia-Inducible Factor 1
  • Hypoxia-Inducible Factor 1, alpha Subunit
  • In Vitro Techniques
  • Lymphokines / pharmacology
  • Mice
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Models, Biological
  • Nuclear Proteins / genetics
  • Nuclear Proteins / physiology*
  • Pregnancy
  • Receptors, Aryl Hydrocarbon*
  • Transcription Factors / genetics
  • Transcription Factors / physiology
  • Vascular Endothelial Growth Factor A
  • Vascular Endothelial Growth Factors
  • Yolk Sac / cytology

Substances

  • Arnt protein, mouse
  • Cytokines
  • DNA-Binding Proteins
  • Endothelial Growth Factors
  • Hif1a protein, mouse
  • Hypoxia-Inducible Factor 1
  • Hypoxia-Inducible Factor 1, alpha Subunit
  • Lymphokines
  • Nuclear Proteins
  • Receptors, Aryl Hydrocarbon
  • Transcription Factors
  • Vascular Endothelial Growth Factor A
  • Vascular Endothelial Growth Factors
  • Aryl Hydrocarbon Receptor Nuclear Translocator