Objective: In the search of new human genotoxic biomarkers, the single cell gel electrophoresis assay has been proposed as a sensible alternative.
Material and methods: This technique detects principally single strand breaks as well as alkali-labile and repair-retarded sites.
Results: Herein we present our experience using the single cell gel electrophoresis assay in human population studies, both occupationally and environmentally exposed.
Conclusions: We discuss the assay feasibility as a genotoxic biomarker.