A novel presenilin 1 missense mutation (L153V) segregating with early-onset autosomal dominant Alzheimer's disease

Hum Mutat. 2000 Jul;16(1):95. doi: 10.1002/1098-1004(200007)16:1<95::AID-HUMU28>3.0.CO;2-H.
No abstract available

MeSH terms

  • Adult
  • Alzheimer Disease / epidemiology
  • Alzheimer Disease / genetics*
  • Amino Acid Substitution / genetics*
  • Female
  • France / epidemiology
  • Genes, Dominant / genetics*
  • Humans
  • Leucine / genetics
  • Male
  • Membrane Proteins / genetics*
  • Mutation, Missense / genetics*
  • Presenilin-1
  • Valine / genetics

Substances

  • Membrane Proteins
  • PSEN1 protein, human
  • Presenilin-1
  • Leucine
  • Valine