The scientific and practical aspects of medical and psychophysiological professional orientation in teenagers and young people have become more and more pressing due to their poorer health along with higher demands for their resistance to unfavourable factors. The aid of a physician and a psychophysiologist in their choice of a future profession promotes the prevention of general and occupational morbidity. Work on professional orientation should be began at school in the 5th-6th and done through school life during which they get a general and vocational education. Guidelines have been developed for effective medical and physiological professional counselling.