Antigen specificity of T-cell response to Mycobacterium avium infection in mice

Infect Immun. 2000 Aug;68(8):4805-10. doi: 10.1128/IAI.68.8.4805-4810.2000.

Abstract

T cells from Mycobacterium avium-infected C57BL/6 mice reacted to culture filtrate, envelope, and cytosol proteins and to fractions obtained from these proteins. Multiple targets were recognized, such as 29- to 45-kDa and <21-kDa antigens of the culture filtrate, antigens of around 30 kDa in the envelope and cytosol, and 45- to 116-kDa proteins in the envelope.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acquired Immunodeficiency Syndrome / microbiology
  • Animals
  • Antigens, Bacterial / immunology*
  • Antigens, Bacterial / isolation & purification
  • Bacterial Proteins / immunology*
  • Bacterial Proteins / isolation & purification
  • Electrophoresis, Polyacrylamide Gel
  • Female
  • Humans
  • Mice
  • Mice, Inbred C57BL
  • Mycobacterium avium / immunology*
  • T-Lymphocytes / immunology*
  • Tuberculosis / immunology*

Substances

  • Antigens, Bacterial
  • Bacterial Proteins