Effect of sleep stages on synchronized spontaneous otoacoustic emissions in pre-term neonates

Clin Neurophysiol. 2000 Aug;111(8):1498-504. doi: 10.1016/s1388-2457(00)00348-5.

Abstract

Objectives: In infants, auditory tests are mainly performed during sleep, since they spend most of their time asleep, and because quiet is required for the duration of the recording session to obtain a precise and reliable response. The aim of this study was to investigate the effect of sleep stages on synchronized spontaneous otoacoustic emissions (sSOAEs) in pre-term neonates at the age where the sleep states begin to be well established and auditory screening can be performed in a neonatology unit before discharge.

Methods: Synchronized SOAEs were repeatedly recorded during a polygraphic sleep recording using the Otodynamic ILO88 system in 10 pre-term neonates at 36 weeks post-conception.

Results: Variations of sSOAE peak numbers occurred in each subject during the recording session. There was no clear relation between sSOAE peak number fluctuations and the different sleep stages.

Conclusions: The sSOAE variations appeared to be closely related to experimental conditions, i.e. the mean background noise level. sSOAEs with the highest amplitude were always recorded; however, those with the smallest amplitude were the first to disappear from the recordings with higher background noise.

MeSH terms

  • Acoustic Stimulation*
  • Female
  • Hearing Disorders / diagnosis
  • Humans
  • Infant, Newborn
  • Infant, Premature*
  • Male
  • Neonatal Screening*
  • Otoacoustic Emissions, Spontaneous*
  • Polysomnography
  • Sleep Stages / physiology*