Percutaneous transluminal coronary angioplasty was first introduced in 1977 by Gruentzig and now provides the option of nonsurgical revascularization for up to 1/2 of patients who undergo diagnostic catheterization for coronary artery disease. Today, although there have been great improvements in technology and operator experience, complications still occur during coronary angiography and revascularization. Coronary dissection, one of the most frequently occurring complications during angiography and angioplasty, occurs in various forms. However, right coronary dissection and retrograde extension to the aortic sinus of Valsalva is extremely unusual during an interventional procedure. We report such an unusual complication which occurred during balloon angioplasty and which was successfully managed by coronary stenting. This unusual complication may have potential risk of quickly involving the entire aorta, causing acute severe aortic regurgitation, acute myocardial infarction, requiring emergency surgery, and even resulting in death. Therefore, prompt diagnosis and management of this complication are very important.