Verbal learning strategies in Parkinson's disease

Neuropsychology. 2000 Jul;14(3):456-70. doi: 10.1037//0894-4105.14.3.456.

Abstract

Word-list learning was studied in patients with Parkinson's disease (PD) and normal control (NC) participants by means of the selective-reminding procedure of H. Buschke and P. A. Fuld (1974) in 3 learning conditions using semantically unrelated items; semantically related items, whose implicit categorical structure had to be spontaneously guessed; and semantically related items, whose explicit categorical structure was known in advance. The PD patients displayed poor learning in all 3 conditions. To identify the functional locus of the PD patients' deficits, the authors performed a stochastic Markov chain analysis, which allowed individual measurements of encoding, retrieval, and category clustering abilities. PD patients were never significantly impaired in encoding word engrams; their impairment was confined to automatic and intentional retrieval and to the ability to benefit from explicit semantic clues.

Publication types

  • Clinical Trial

MeSH terms

  • Aged
  • Female
  • Humans
  • Male
  • Markov Chains
  • Mental Recall
  • Middle Aged
  • Models, Psychological
  • Multivariate Analysis
  • Neuropsychological Tests
  • Parkinson Disease / psychology*
  • Verbal Learning / physiology*