Polymerase chain reaction-single-strand conformation polymorphism based determination of two major genetic defects responsible for a phenotypic polymorphism of cytochrome P450 (CYP) 2C19 in the Japanese population

Anal Biochem. 2000 Aug 15;284(1):160-2. doi: 10.1006/abio.2000.4671.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Alleles
  • Aryl Hydrocarbon Hydroxylases*
  • Cytochrome P-450 CYP2C19
  • Cytochrome P-450 Enzyme System / blood
  • Cytochrome P-450 Enzyme System / genetics*
  • Humans
  • Japan
  • Mixed Function Oxygenases / blood
  • Mixed Function Oxygenases / genetics*
  • Mutation
  • Phenotype
  • Polymerase Chain Reaction / methods*
  • Polymorphism, Restriction Fragment Length
  • Polymorphism, Single-Stranded Conformational*

Substances

  • Cytochrome P-450 Enzyme System
  • Mixed Function Oxygenases
  • Aryl Hydrocarbon Hydroxylases
  • CYP2C19 protein, human
  • Cytochrome P-450 CYP2C19