Tracing the evolution of vertebrate fibrillar collagens from an ancestral alpha chain

Matrix Biol. 2000 Jul;19(3):275-9. doi: 10.1016/s0945-053x(00)00067-6.

Abstract

From considerations of gene structure, phylogenetic analysis, modular organisation of related proteins and fibril shapes, we suggest a model for the evolution of contemporary vertebrate fibrillar collagens from a common ancestral alpha chain.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Collagen / genetics*
  • Evolution, Molecular*
  • Humans
  • Procollagen / genetics*
  • Protein Structure, Tertiary
  • Vertebrates

Substances

  • Procollagen
  • Collagen