YC-1, an activation inductor of soluble guanylyl cyclase

Acta Crystallogr C. 2000 Aug:56 ( Pt 8):1035-6. doi: 10.1107/s0108270100007393.

Abstract

The crystal structure of 1-benzyl-3-(5-hydroxymethyl-2-furyl)indazole, C(19)H(16)N(2)O(2), showed that the furan O and indazole N atoms lie on the same face of the molecule. The crystal packing consists of intermolecular hydrogen bonding, and indazole-indazole and indazole-phenyl interactions.

MeSH terms

  • Crystallography, X-Ray
  • Enzyme Activators / chemistry*
  • Guanylate Cyclase / biosynthesis*
  • Hydrogen Bonding
  • Indazoles / chemistry*
  • Models, Molecular
  • Molecular Conformation

Substances

  • Enzyme Activators
  • Indazoles
  • 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole
  • Guanylate Cyclase