Abstract
Epidemiological evidence from the early 1990s suggested that a sexually transmitted infectious agent other than the HIV virus was associated with the development of Kaposi's sarcoma in patients with HIV. A novel gamma herpesvirus was identified in Kaposi's sarcoma lesions. The molecular genetics of this virus are reviewed in this article.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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AIDS-Related Opportunistic Infections / virology*
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CASP8 and FADD-Like Apoptosis Regulating Protein
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Carrier Proteins / genetics
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Cyclin D
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Cyclins / genetics
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Genes, bcl-2 / genetics
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Herpesvirus 8, Human / genetics*
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Humans
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Interleukin-6 / genetics
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Intracellular Signaling Peptides and Proteins*
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Macrophage Inflammatory Proteins / genetics
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Receptors, Cell Surface / genetics
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Sarcoma, Kaposi / virology*
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Skin Neoplasms / virology*
Substances
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CASP8 and FADD-Like Apoptosis Regulating Protein
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CFLAR protein, human
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Carrier Proteins
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Cyclin D
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Cyclins
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Interleukin-6
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Intracellular Signaling Peptides and Proteins
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Macrophage Inflammatory Proteins
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Receptors, Cell Surface