Interactions between Listeria monocytogenes and host mammalian cells

Microbes Infect. 2000 Jun;2(7):803-11. doi: 10.1016/s1286-4579(00)90365-4.

Abstract

Bacterial pathogens have developed a variety of strategies to induce their own internalization into mammalian cells which are normally nonphagocytic. The Gram-positive bacterium Listeria monocytogenes enters into many cultured cell types using two bacterial surface proteins, InlA (internalin) and InlB. In both cases, entry takes place after engagement of a receptor and induction of a series of signaling events.

Publication types

  • Review

MeSH terms

  • Animals
  • Bacterial Proteins / chemistry
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism
  • Cadherins / metabolism
  • Humans
  • Listeria monocytogenes / metabolism
  • Listeria monocytogenes / pathogenicity*
  • Listeria monocytogenes / physiology
  • Mammals
  • Membrane Proteins / chemistry
  • Membrane Proteins / metabolism
  • Multigene Family
  • Phosphatidylinositol 3-Kinases / metabolism
  • Signal Transduction

Substances

  • Bacterial Proteins
  • Cadherins
  • Membrane Proteins
  • inlB protein, Listeria monocytogenes
  • internalin protein, Bacteria
  • Phosphatidylinositol 3-Kinases