Abstract
We report a case of ischemic cholangitis that occurred after transcatheter hepatic arterial chemoembolization (TAE). Ten months prior to TAE the patient had undergone central bisegmentectomy for hepatocellular carcinoma with resection of the extrahepatic bile duct. Eleven days after TAE, he developed suppurative cholangitis and multiple organ failure. Prior surgical ligation of the peribiliary arteries around the extrahepatic bile duct followed by TAE was considered to have played a crucial role in the development of ischemic cholangitis. This case demonstrates the importance of blood flow from the peribiliary arteries for the survival of the biliary epithelium.
MeSH terms
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Angiography
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Antineoplastic Combined Chemotherapy Protocols / administration & dosage
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Antineoplastic Combined Chemotherapy Protocols / adverse effects*
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Bile Duct Neoplasms / diagnosis
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Bile Duct Neoplasms / drug therapy
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Bile Duct Neoplasms / surgery
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Bile Ducts, Extrahepatic / surgery*
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Bile Ducts, Intrahepatic / blood supply*
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Carcinoma, Hepatocellular / diagnosis
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Carcinoma, Hepatocellular / drug therapy
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Carcinoma, Hepatocellular / surgery
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Carcinoma, Papillary / diagnosis
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Carcinoma, Papillary / drug therapy
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Carcinoma, Papillary / surgery
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Chemoembolization, Therapeutic / adverse effects*
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Cholangitis / chemically induced*
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Cholangitis / diagnosis
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Cholangitis / surgery
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Hepatic Artery
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Humans
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Injections, Intra-Arterial
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Ischemia / chemically induced*
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Ischemia / diagnosis
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Ischemia / surgery
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Liver Neoplasms / diagnosis
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Liver Neoplasms / drug therapy
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Liver Neoplasms / surgery
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Magnetic Resonance Imaging
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Male
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Middle Aged
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Neoplasm Recurrence, Local
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Neoplasms, Multiple Primary / diagnosis
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Neoplasms, Multiple Primary / drug therapy
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Neoplasms, Multiple Primary / surgery
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Suction
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Tomography, X-Ray Computed