Abstract
A boy with chronic active Epstein-Barr virus infection (EBV) developed bilateral exophthalmos by infiltrating EBV-infected natural-killer cells during combined chemotherapy. This unusual presentation resolved completely after allogeneic bone-marrow transplantation, and EBV-infected peripheral T and natural-killer cells were also eradicated.
MeSH terms
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Antiviral Agents / therapeutic use
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Bone Marrow Transplantation
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Child
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Chronic Disease
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Epstein-Barr Virus Infections / therapy*
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Exophthalmos / virology
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Glucocorticoids / therapeutic use
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Hematopoietic Stem Cell Transplantation*
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Humans
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Immunosuppressive Agents / therapeutic use
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Killer Cells, Natural / virology
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Lymphoproliferative Disorders / therapy
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Lymphoproliferative Disorders / virology*
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Male
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Oculomotor Muscles / virology
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T-Lymphocytes / virology
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Transplantation Conditioning
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Transplantation, Homologous
Substances
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Antiviral Agents
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Glucocorticoids
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Immunosuppressive Agents