Free radical scavenging activity of Lafoensia pacari

J Ethnopharmacol. 2000 Sep;72(1-2):173-8. doi: 10.1016/s0378-8741(00)00233-6.

Abstract

The methanolic extract of the stem bark of Lafoensia pacari (Lythraceae) showed free radical scavenging activity in the diphenyl picryl hydrazyl radical (DPPH) decoloration assay and inhibited the enzyme xanthine oxidase 'in vitro'. Bioassay-guided isolation led to ellagic acid (EA) as the main active compound of Brazilian and Paraguayan collections of the plant.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alcohols
  • Brazil
  • Chromatography, High Pressure Liquid
  • Free Radical Scavengers / isolation & purification
  • Free Radical Scavengers / pharmacology*
  • Free Radicals / chemistry
  • Plant Epidermis / chemistry
  • Plant Extracts / pharmacology
  • Plant Stems / chemistry
  • Plants, Medicinal / chemistry*
  • Spectrophotometry, Ultraviolet
  • Water
  • Xanthine Oxidase / metabolism

Substances

  • Alcohols
  • Free Radical Scavengers
  • Free Radicals
  • Plant Extracts
  • Water
  • Xanthine Oxidase