One hundred consecutive minimally invasive parathyroid explorations

Ann Surg. 2000 Sep;232(3):331-9. doi: 10.1097/00000658-200009000-00005.

Abstract

Objective: To review the outcomes of 100 consecutive minimally invasive parathyroid explorations.

Summary background data: Minimally invasive parathyroidectomy (MIP) has challenged the traditional approach of bilateral neck exploration for patients with primary hyperparathyroidism. Most patients with primary hyperparathyroidism have a single adenoma that when resected results in cure. It therefore appears logical to perform a directed approach to adenoma extirpation. MIP involves high-quality sestamibi images obtained with single photon emission computed tomography to localize enlarged parathyroid glands in three dimensions, limited exploration after surgeon-administered cervical block anesthesia, rapid intraoperative parathyroid hormone assay to confirm the adequacy of resection, and discharge within 1 to 3 hours of surgery.

Methods: MIP was offered to 100 selected consecutive patients during an 18-month period beginning in March 1998.

Results: Ninety-two cases were accomplished under cervical block anesthesia and 89 of these on an ambulatory basis. The cure rate was 100%, and there were no long-term complications. The mean hospital charge for MIP was less than 40% of that associated with traditional exploration.

Conclusions: Outpatient MIP appears to be the procedure of choice for most patients with primary hyperparathyroidism.

MeSH terms

  • Adenoma / diagnostic imaging
  • Adenoma / surgery*
  • Adult
  • Ambulatory Surgical Procedures
  • Humans
  • Hyperparathyroidism / diagnostic imaging
  • Hyperparathyroidism / surgery*
  • Minimally Invasive Surgical Procedures*
  • Parathyroid Hormone / blood
  • Parathyroid Neoplasms / diagnostic imaging
  • Parathyroid Neoplasms / surgery*
  • Parathyroidectomy*
  • Technetium Tc 99m Sestamibi
  • Tomography, Emission-Computed, Single-Photon

Substances

  • Parathyroid Hormone
  • Technetium Tc 99m Sestamibi