Polymeric IgA myeloma, hyperlipidaemia and xanthomatosis: a further case and review

Postgrad Med J. 1975 Jan;51(591):44-51. doi: 10.1136/pgmj.51.591.44.

Abstract

A patient is described who had myeloma of the polymeric IgA variety, together with a striking hyperlipidaemia and xanthomatosis. Investigations into the protein and lipid abnormality failed to demonstrate any mechanism for the hyperlipidaemia. A review of the literature, however, validates this clinical entity and some of the suggested explanations are discussed.

Publication types

  • Review

MeSH terms

  • Abdomen
  • Cyclophosphamide / therapeutic use
  • Elbow
  • Humans
  • Hyperlipidemias / complications*
  • Hyperlipidemias / drug therapy
  • Immunoglobulin A
  • Knee
  • Male
  • Middle Aged
  • Multiple Myeloma / complications*
  • Multiple Myeloma / drug therapy
  • Prednisolone / therapeutic use
  • Skin Diseases / complications*
  • Syndrome
  • Thorax
  • Xanthomatosis / complications*

Substances

  • Immunoglobulin A
  • Cyclophosphamide
  • Prednisolone