Purpose: To report an unusual case of bilateral papilledema from a large intracranial epidermoid cyst.
Methods: Case report.
Results: A 26-year-old man presented with visual loss, bilateral papilledema, and only a few neurological symptoms. Magnetic resonance imaging disclosed such a large lesion that his right cerebral hemisphere was compressed to one half its normal size. Histopathologic examination of the completely removed tumor revealed an epidermoid cyst.
Conclusion: This unique case involved a patient with bilateral papilledema caused by a huge intracranial epidermoid cyst. Epidermoid tumors should be considered in the differential diagnosis of papilledema.