A new class of microtubule-associated proteins in plants

Nat Cell Biol. 2000 Oct;2(10):750-3. doi: 10.1038/35036390.

Abstract

In plants there are three microtubule arrays involved in cellular morphogenesis that have no equivalent in animal cells. In animals, microtubules are decorated by another class of proteins - the structural MAPS - which serve to stabilize microtubules and assist in their organization. The best-studied members of this class in plants are the MAP-65 proteins that can be purified together with plant microtubules after several cycles of polymerization and depolymerization. Here we identify three similar MAP-65 complementary DNAs representing a small gene family named NtMAP65-1, which encode a new set of proteins, collectively called NtMAP65-1. We show that NtMAP65-1 protein localizes to areas of overlapping microtubules, indicating that it may function in the behaviour of antiparallel microtubules in the mitotic spindle and the cytokinetic phragmoplast.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Cell Compartmentation
  • DNA, Complementary / genetics
  • DNA, Plant / genetics
  • Fluorescent Antibody Technique
  • Microtubule-Associated Proteins / isolation & purification
  • Molecular Sequence Data
  • Nicotiana / genetics*
  • Plant Proteins / genetics*
  • Plant Proteins / isolation & purification
  • Plants, Toxic*
  • Sequence Analysis
  • Sequence Homology, Amino Acid

Substances

  • DNA, Complementary
  • DNA, Plant
  • Microtubule-Associated Proteins
  • Plant Proteins

Associated data

  • GENBANK/AJ289862
  • GENBANK/AJ289863
  • GENBANK/AJ289864