Absolute configuration of 1,n-diols by NMR: the importance of the combined anisotropic effects in bis-arylmethoxyacetates

JM Seco; M Martino; E Quinoa; R Riguera

doi:10.1021/ol0062852

Absolute configuration of 1,n-diols by NMR: the importance of the combined anisotropic effects in bis-arylmethoxyacetates

Org Lett. 2000 Oct 19;2(21):3261-4. doi: 10.1021/ol0062852.

Authors

JM Seco¹, M Martino, E Quinoa, R Riguera

Affiliation

¹ Departamento de Quimica Organica, Facultad de Quimica e Instituto de Acuicultura, Universidad de Santiago de Compostela, E-15706 Santiago de Compostela, Spain.

PMID: 11029185
DOI: 10.1021/ol0062852

Abstract

The absolute configuration of a 1,n-diol can be assigned from the (1)H NMR spectra of its (R)- and (S)-AMAA diesters if the chemical shifts are interpreted as the result of the joint action of the two chiral auxiliaries.