Abstract
Three new phenanthrene derivatives, aristoliukine-C, aristofolin-E and aristolochic acid-Ia methyl ester, and one new sesquiterpene, madolin-P, together with 58 known compounds were isolated from the stem and root of Aristolochia kaempferi. The structures of these compounds were determined by spectral analysis. The cytotoxicity and antiplatelet activity of the isolated compounds are also discussed.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents, Phytogenic / isolation & purification
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Antineoplastic Agents, Phytogenic / pharmacology
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Drug Screening Assays, Antitumor
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Humans
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In Vitro Techniques
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Magnetic Resonance Spectroscopy
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Phenanthrenes / analysis
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Phenanthrenes / isolation & purification
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Plant Extracts / chemistry
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Plant Extracts / pharmacology
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Plant Roots / chemistry
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Plant Stems / chemistry
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Plants, Medicinal / chemistry*
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Platelet Aggregation Inhibitors / pharmacology
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Sesquiterpenes / analysis
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Sesquiterpenes / isolation & purification
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Spectrometry, Mass, Fast Atom Bombardment
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Spectrophotometry, Infrared
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Spectrophotometry, Ultraviolet
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Taiwan
Substances
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Antineoplastic Agents, Phytogenic
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Phenanthrenes
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Plant Extracts
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Platelet Aggregation Inhibitors
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Sesquiterpenes