Acute tubular necrosis induced by high level of cyclosporine A in a lung transplant

Transplantation. 2000 Oct 27;70(8):1234-6. doi: 10.1097/00007890-200010270-00018.

Abstract

We report a case of acute accidental cyclosporine A intoxication in a lung transplant patient. The intoxication led to renal failure due to acute tubular necrosis, which was partially reversible. A review of the literature on the renal consequences of cyclosporine A intoxication is given.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cyclosporine / administration & dosage
  • Cyclosporine / poisoning*
  • Dose-Response Relationship, Drug
  • Drug Overdose / etiology
  • Humans
  • Kidney Tubular Necrosis, Acute / chemically induced*
  • Lung Transplantation*
  • Male

Substances

  • Cyclosporine