Hypernatraemia in early infancy

Ann Trop Paediatr. 2000 Sep;20(3):173-7; discussion 177-8. doi: 10.1080/02724936.2000.11748129.

Abstract

Hypernatraemia, defined as serum sodium > 150 mmol/l, is still seen frequently in tropical environments. We describe two infants, one with poor fluid intake and excessive wrapping and the other with a high solute intake, both of whom presented in a state of severe hypernatraemia. The pathophysiology of this condition is outlined, as are the major causes, such as sodium overload, inadequate water intake, increased water loss of non-renal origin, increased water loss of renal origin and essential hypernatraemia. The literature is reviewed and the current basis for management is appraised and discussed.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Dehydration / complications
  • Humans
  • Hypernatremia / etiology*
  • Hypernatremia / therapy
  • Infant Care
  • Infant Food / adverse effects
  • Infant, Newborn
  • Male