[Primary central nervous system malignant lymphoma originating from the cerebellum and extending along the lower cranial nerves]

No Shinkei Geka. 2000 Oct;28(10):879-83.
[Article in Japanese]

Abstract

We report a case of primary central nervous system (CNS) malignant lymphoma of the central nervous system originating from the cerebellum and growing along the lower cranial nerves. A 67-year-old woman presented with hoarseness, vertigo, nausea, and vomiting. Gd-DTPA enhanced MRI showed a homogeneous enhanced mass lesion extending from the cerebellum to the medulla oblongata around the jugular foramen on the right side. Although pre- and intra-operative diagnosis had been schwannoma, histopathological examination revealed a B-cell, diffuse malignant lymphoma. The growth pattern of malignant lymphoma in the present case, which extended extra-axially, is considered to be rare. We discuss here the growth patterns and difficulties of diagnosis of primary CNS malignant lymphoma in this area.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Brain / pathology
  • Central Nervous System Neoplasms / pathology*
  • Central Nervous System Neoplasms / surgery
  • Cerebellar Neoplasms / pathology*
  • Cerebellar Neoplasms / surgery
  • Combined Modality Therapy
  • Cranial Irradiation
  • Cranial Nerve Neoplasms / pathology*
  • Cranial Nerve Neoplasms / surgery
  • Female
  • Humans
  • Lymphoma, B-Cell / pathology*
  • Lymphoma, B-Cell / surgery
  • Lymphoma, Non-Hodgkin / pathology*
  • Lymphoma, Non-Hodgkin / surgery
  • Magnetic Resonance Imaging