Acarbose and lymphocytic colitis

Lancet. 2000 Oct 7;356(9237):1246. doi: 10.1016/s0140-6736(00)02797-5.

Abstract

We report a case of lymphocytic colitis induced by acarbose. Our immunopathological findings shown before and after rechallenge are consistent with a colonic immune-cell activation by the drug.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Acarbose / adverse effects*
  • Colitis / chemically induced*
  • Colitis / pathology
  • Colon / chemistry
  • Colon / pathology
  • HLA-DR Antigens / analysis
  • Humans
  • Hypoglycemic Agents / adverse effects*
  • Immunohistochemistry
  • Lymphocytes / drug effects*
  • Lymphocytes / pathology
  • Male
  • Middle Aged
  • Receptors, Interleukin-2 / analysis

Substances

  • HLA-DR Antigens
  • Hypoglycemic Agents
  • Receptors, Interleukin-2
  • Acarbose