Synthesis of cis and trans isomers of an isoxazoline ring-hydroxylated metabolite of roxifiban, a platelet glycoprotein IIb/IIIa receptor antagonist

J Org Chem. 2000 Nov 17;65(23):8100-4. doi: 10.1021/jo000755o.
No abstract available

MeSH terms

  • Amidines / metabolism*
  • Animals
  • Dogs
  • Humans
  • Isoxazoles / metabolism*
  • Platelet Glycoprotein GPIIb-IIIa Complex / antagonists & inhibitors*
  • Rats

Substances

  • Amidines
  • Isoxazoles
  • Platelet Glycoprotein GPIIb-IIIa Complex
  • roxifiban