Effect of angiotensin-converting enzyme inhibitor (enalapril or imidapril) on ventilation during exercise in patients with chronic heart failure secondary to idiopathic dilated cardiomyopathy

Am J Cardiol. 2000 Mar 1;85(5):658-60, A10. doi: 10.1016/s0002-9149(99)00830-9.

Abstract

Eighteen patients with heart failure were studied to clarify whether angiotensin-converting enzyme inhibitor treatment improves excess ventilation during exercise. Treatment with angiotensin-converting enzyme inhibitors had a beneficial effect on excess ventilation during exercise, without significant improvement in exercise capacity in patients with moderate congestive heart failure.

MeSH terms

  • Angiotensin-Converting Enzyme Inhibitors / pharmacology*
  • Angiotensin-Converting Enzyme Inhibitors / therapeutic use
  • Cardiomyopathy, Dilated / complications*
  • Enalapril / pharmacology*
  • Enalapril / therapeutic use
  • Exercise Test
  • Exercise Tolerance / drug effects
  • Heart Failure / drug therapy*
  • Heart Failure / etiology
  • Humans
  • Imidazoles / pharmacology*
  • Imidazoles / therapeutic use
  • Imidazolidines*
  • Middle Aged
  • Pulmonary Ventilation / drug effects*
  • Time Factors

Substances

  • Angiotensin-Converting Enzyme Inhibitors
  • Imidazoles
  • Imidazolidines
  • Enalapril
  • imidapril