The causes of Pregnancy Induced Hypertension are still under study. A genetic cause has been suggested as well as raised activity of the blood lipid system, which is however determined genetically. One element of the lipid system is lipoprotein a, which may have a key role in prediction of preeclampsia. The aim of our study was to determine lipoprotein (a) concentration in women with preeclampsia and in healthy pregnancies, and to assess the usefulness of lipoprotein (a) concentration as prognostic factor of eclampsia. Sera from 19 women with preeclampsia and from 19 with healthy pregnancies were tested. Our results show that determination of lipoprotein (a) levels in preeclampsia may be significant as predictive factor of eclampsia.