IS1607, a single-copy insertion sequence-related element of the Mycobacterium tuberculosis complex

J Dziadek; I Wolinska; A Sajduda; A Dela; J J McFadden

IS1607, a single-copy insertion sequence-related element of the Mycobacterium tuberculosis complex

Int J Tuberc Lung Dis. 2000 Nov;4(11):1078-81.

Authors

J Dziadek¹, I Wolinska, A Sajduda, A Dela, J J McFadden

Affiliation

¹ Centre for Microbiology and Virology, Polish Academy of Sciences, Lódz, Poland. [email protected]

PMID: 11092722

Abstract

The species specificity of IS1607, a new Mycobacterium tuberculosis complex insertion sequence-related element, was investigated. IS1607 was present as a single copy in M. tuberculosis, M. bovis and M. bovis BCG strains. This sequence also existed in M. africanum and M. microti, but was not present in 69 strains of 19 atypical mycobacterial species analyzed by using polymerase chain reaction (PCR) or Southern hybridization assay. IS1607 appears to be specific for the M. tuberculosis complex.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

DNA Transposable Elements*
Mycobacterium bovis / genetics*
Mycobacterium tuberculosis / genetics*
Nontuberculous Mycobacteria / genetics
Open Reading Frames
Polymerase Chain Reaction
Species Specificity

Substances

DNA Transposable Elements