TRES: comparative promoter sequence analysis

Bioinformatics. 2000 Aug;16(8):739-40. doi: 10.1093/bioinformatics/16.8.739.

Abstract

Comparative promoter analysis is a promising strategy for elucidation of common regulatory modules conserved in evolutionarily related sequences or in genes showing common expression profiles. To facilitate such analysis, we have developed a software tool that detects conserved transcription factor binding sites, cis-elements, palindromes and k-tuples simultaneously in a set of sequences, and thus helps to identify putative motifs for designing further experiments.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Binding Sites
  • Humans
  • Promoter Regions, Genetic*
  • Sequence Analysis, DNA / methods*
  • Software*
  • Transcription Factors / metabolism

Substances

  • Transcription Factors