A comparison of signal sequence prediction methods using a test set of signal peptides

K M Menne; H Hermjakob; R Apweiler

doi:10.1093/bioinformatics/16.8.741

A comparison of signal sequence prediction methods using a test set of signal peptides

Bioinformatics. 2000 Aug;16(8):741-2. doi: 10.1093/bioinformatics/16.8.741.

Authors

K M Menne¹, H Hermjakob, R Apweiler

Affiliation

¹ EMBL Outstation Hinxton - The European Bioinformatics Institute (EBI), Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.

PMID: 11099261
DOI: 10.1093/bioinformatics/16.8.741

Abstract

We describe the creation of a test set containing secretory and non-secretory proteins. Five existing prediction programs for signal sequences and their cleavage sites are compared on the basis of this test set: SPScan, SigCleave, SignalP V1.1, SignalP V2.0. b2-HMM and SignalP V2.0.b2-NN.

Publication types

Comparative Study

MeSH terms

Protein Sorting Signals*
Software*

Substances

Protein Sorting Signals