7-Nitro-1H-indazole, an inhibitor of nitric oxide synthase

Acta Crystallogr C. 2000 Dec;56(Pt 12):1503-4. doi: 10.1107/s0108270100012956.

Abstract

The crystal structure of 7-nitro-1H-indazole, C(7)H(5)N(3)O(2), an inhibitor of nitric oxide synthase, shows the existence of an intramolecular hydrogen bond between an O atom of the nitro group and the NH group of the indazole ring. The crystal packing consists of intermolecular hydrogen bonding and indazole.indazole interactions.

MeSH terms

  • Crystallography, X-Ray
  • Enzyme Inhibitors / chemistry*
  • Hydrogen Bonding
  • Indazoles / chemistry*
  • Molecular Structure
  • Nitric Oxide Synthase / antagonists & inhibitors*

Substances

  • Enzyme Inhibitors
  • Indazoles
  • Nitric Oxide Synthase
  • 7-nitroindazole