Clear cell adenocarcinoma with endobronchial polypoid growth

Pathol Int. 2000 Dec;50(12):979-83. doi: 10.1046/j.1440-1827.2000.01140.x.

Abstract

Clear cell adenocarcinoma of the lung is extremely rare. On radiography, a 45-year-old female with fever was found to have an abnormal shadow in the left lower lung field. Bronchoscopy revealed a polypoid tumor in the left bronchus. On biopsy, the tumor was determined to be adenocarcinoma. Preoperative examination found no tumors outside of the lung. The patient underwent left lower lobectomy with bronchial wedge resection. The tumor had completely obstructed and dilated the left lower bronchus, but had not invaded the tissue outside the bronchial wall. Microscopically, the cytoplasm of the tumor cells contained abundant glycogen, and the tumor had solid and glandular structures. The tumor was diagnosed as clear cell adenocarcinoma of the lung.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenocarcinoma, Clear Cell / metabolism
  • Adenocarcinoma, Clear Cell / pathology*
  • Adenocarcinoma, Clear Cell / ultrastructure
  • Bronchial Neoplasms / pathology*
  • Female
  • Humans
  • Immunohistochemistry
  • Keratins / analysis
  • Lung Neoplasms / metabolism
  • Lung Neoplasms / pathology*
  • Lung Neoplasms / ultrastructure
  • Male
  • Microscopy, Electron
  • Middle Aged
  • Mucin-1 / analysis
  • Polyps / pathology*

Substances

  • Mucin-1
  • Keratins