CluSTr: a database of clusters of SWISS-PROT+TrEMBL proteins

Nucleic Acids Res. 2001 Jan 1;29(1):33-6. doi: 10.1093/nar/29.1.33.

Abstract

The CluSTr (Clusters of SWISS-PROT and TrEMBL proteins) database offers an automatic classification of SWISS-PROT and TrEMBL proteins into groups of related proteins. The clustering is based on analysis of all pairwise comparisons between protein sequences. Analysis has been carried out for different levels of protein similarity, yielding a hierarchical organisation of clusters. The database provides links to InterPro, which integrates information on protein families, domains and functional sites from PROSITE, PRINTS, Pfam and ProDom. Links to the InterPro graphical interface allow users to see at a glance whether proteins from the cluster share particular functional sites. CluSTr also provides cross-references to HSSP and PDB. The database is available for querying and browsing at http://www.ebi.ac.uk/clustr.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Carrier Proteins / genetics
  • Databases, Factual*
  • Humans
  • Information Services
  • Internet
  • Proteins* / genetics
  • Sequence Alignment
  • Sodium / metabolism

Substances

  • Carrier Proteins
  • Proteins
  • Sodium