Cellular delivery of trophic factors for the treatment of Huntington's disease: is neuroprotection possible?

Prog Brain Res. 2000:127:414-30.

Authors

J H Kordower¹, O Isacson, L Leventhal, D F Emerich

Affiliation

¹ Research Center for Brain Repair and Department of Neurological Sciences, Rush Presbyterian Medical Center, 2242 West Harrison Street, Chicago, IL 60612, USA. [email protected]

PMID: 11142039

No abstract available

Publication types

Review

MeSH terms

Animals
Brain Tissue Transplantation*
Cell- and Tissue-Based Therapy
Cells, Cultured / transplantation
Ciliary Neurotrophic Factor / pharmacology
Ciliary Neurotrophic Factor / therapeutic use
Disease Models, Animal
Drug Delivery Systems / methods*
Graft Survival / physiology
Humans
Huntington Disease / pathology
Huntington Disease / physiopathology
Huntington Disease / surgery*
Neostriatum / pathology
Neostriatum / physiopathology
Neostriatum / surgery
Nerve Growth Factor / pharmacology
Nerve Growth Factor / therapeutic use
Nerve Growth Factors / therapeutic use*
Neuroprotective Agents / therapeutic use*

Substances

Ciliary Neurotrophic Factor
Nerve Growth Factors
Neuroprotective Agents
Nerve Growth Factor