Multiphase ECG-triggered 3D contrast-enhanced MR angiography: utility for evaluation of hilar and mediastinal invasion of bronchogenic carcinoma

J Magn Reson Imaging. 2001 Feb;13(2):215-24. doi: 10.1002/1522-2586(200102)13:2<215::aid-jmri1032>3.0.co;2-2.

Abstract

The purpose of this study was to evaluate the usefulness of cardiac synchronized magnetic resonance angiography [electrocardiographically (ECG)-triggered MRA] for improving image quality and detection of hilar and mediastinal invasion of bronchogenic carcinoma. Fifty patients, suspected of having hilar or mediastinal invasion of bronchogenic carcinoma, underwent contrast-enhanced computed tomography and MR imaging including conventional and ECG-triggered MRA. Twenty patients subsequently also underwent surgical resection. Vascular enhancement-to-background ratio (VBR), vascular enhancement-to-tumor ratio (VTR), signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) and image quality scores of thoracic vessels obtained with both MRA techniques were determined and compared. In addition, the diagnostic accuracy of tumor invasion of pulmonary vessels was compared. VBRs and VTRs of both MRA techniques were not significantly different. ECG-triggered MRA significantly improved SNRs and CNRs (P < 0.05). Two readers judged that overall image quality of ECG-triggered MRA was better than that of conventional MRA (kappa > or = 0.41). In conclusion, ECG-triggered MRA improves the image quality and the detection of hilar and mediastinal invasion of bronchogenic carcinoma.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Carcinoma, Bronchogenic / blood supply
  • Carcinoma, Bronchogenic / diagnosis
  • Carcinoma, Bronchogenic / secondary*
  • Carcinoma, Non-Small-Cell Lung / blood supply
  • Carcinoma, Non-Small-Cell Lung / diagnosis
  • Carcinoma, Non-Small-Cell Lung / secondary*
  • Electrocardiography*
  • Female
  • Humans
  • Image Enhancement*
  • Imaging, Three-Dimensional*
  • Lung Neoplasms / blood supply
  • Lung Neoplasms / diagnosis*
  • Lymphatic Metastasis
  • Magnetic Resonance Angiography*
  • Male
  • Mediastinal Neoplasms / blood supply
  • Mediastinal Neoplasms / diagnosis
  • Mediastinal Neoplasms / secondary*
  • Middle Aged
  • Neoplasm Invasiveness
  • Predictive Value of Tests
  • Pulmonary Artery / pathology*
  • Vascular Neoplasms / diagnosis
  • Vascular Neoplasms / pathology
  • Vascular Neoplasms / secondary*