Abstract
Fractionation of an ethanolic extract of the leaves of Phenax angustifolius has resulted in the isolation of two new lignans, 2-hydroxy-2-(3',4'-dihydroxyphenyl)methyl-3-(3' ',4' '-dimethoxyphenyl)methyl-gamma-butyrolactone (1) and 2-hydroxy-2-(4'-O-beta-D-glucopyranosyl-3'-hydroxyphenyl)methyl-3-(3' ',4' '-dimethoxyphenyl)methyl-gamma-butyrolactone (2), and three known compounds, vitexin, isovitexin, and quercetin 3-O-alpha-L-rhamnopyranoside. The structures of 1 and 2 were determined using spectroscopic methods.
MeSH terms
-
Chromatography, High Pressure Liquid
-
Circular Dichroism
-
Glucosides / chemistry*
-
Glucosides / isolation & purification
-
Lignans / chemistry*
-
Lignans / isolation & purification
-
Magnetic Resonance Spectroscopy
-
Phenols / chemistry*
-
Phenols / isolation & purification
-
Plant Extracts / analysis
-
Plant Leaves / chemistry*
-
Plants, Medicinal / chemistry*
-
Spectrometry, Mass, Electrospray Ionization
Substances
-
2-hydroxy-2-(3',4'-dihydroxyphenyl)methyl-3-(3'',4''-dimethoxyphenyl)methylbutyrolactone
-
2-hydroxy-2-(4'-O-glucopyranosyl-3'-hydroxyphenyl)methyl-3-(3'',4''-dimethoxyphenyl)methylbutyrolactone
-
Glucosides
-
Lignans
-
Phenols
-
Plant Extracts