Abstract
Non-Hodgkin lymphomas associated with acquired immunodeficiency syndrome are heterogeneous. Recently, a novel subtype of non-Hodgkin lymphoma occurring mostly in patients with acquired immunodeficiency syndrome has been described and designated as plasmablastic lymphoma. The histomorphologic and immunophenotypic findings of this distinct subtype of non-Hodgkin lymphoma have been characterized previously. Most patients present with oral cavity involvement. We report a case of plasmablastic lymphoma presenting as a lung tumor. To our knowledge, this is the first case report of this unusual subtype of diffuse large B-cell lymphoma in this location.
MeSH terms
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Acquired Immunodeficiency Syndrome / complications
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Antibodies, Monoclonal
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DNA, Viral / analysis
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Herpesvirus 4, Human / genetics
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Humans
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Immunohistochemistry
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Immunophenotyping
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In Situ Hybridization
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Lung Neoplasms / diagnosis*
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Lung Neoplasms / immunology
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Lung Neoplasms / pathology
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Lung Neoplasms / virology
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Lymphoma, AIDS-Related / diagnosis*
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Lymphoma, AIDS-Related / immunology
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Lymphoma, AIDS-Related / pathology
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Lymphoma, AIDS-Related / virology
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Lymphoma, B-Cell / diagnosis*
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Lymphoma, B-Cell / pathology
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Lymphoma, Large B-Cell, Diffuse / diagnosis*
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Lymphoma, Large B-Cell, Diffuse / pathology
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Male
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Membrane Glycoproteins / analysis
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Middle Aged
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Plasma Cells / pathology
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Proteoglycans / analysis
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Syndecans
Substances
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Antibodies, Monoclonal
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DNA, Viral
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Membrane Glycoproteins
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Proteoglycans
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Syndecans
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VS38 monoclonal antibody