Sesamin a potent antifeedant principle from Piper mullesua

Phytother Res. 2001 Feb;15(1):70-2. doi: 10.1002/1099-1573(200102)15:1<70::aid-ptr671>3.0.co;2-n.

Abstract

Sesamin, a major lignan of Piper mullesua of Manipur origin, exhibited significant antifeedant activity and moderate growth inhibition towards 4th instar larvae of Spilarctia obliqua. No larval toxicity of sesamin could be established in topical bioassay experiments. Its effective dose for 50% feeding deterrence (ED(50)) and growth inhibition (GI(50)) were found to be 3856 and 6212 ppm, respectively.

MeSH terms

  • Animals
  • Dioxoles / pharmacology*
  • Growth Inhibitors / pharmacology*
  • Insecticides / pharmacology*
  • Larva / drug effects
  • Lepidoptera / drug effects*
  • Lignans / pharmacology*

Substances

  • Dioxoles
  • Growth Inhibitors
  • Insecticides
  • Lignans
  • sesamin